Table 1.
Clinicopathological characteristics of the entire cohort and subgroups.
| Variables | All | VP | VFL | Laryngeal Cancer | p-Value 1 |
|---|---|---|---|---|---|
| Patients | (n = 105) | (n = 37) | (n = 22) | (n = 46) | |
| Clinical characteristics | |||||
| Male sex, n (%) | 93 (89) | 30 (81) | 20 (91) | 43 (94) | 0.20 |
| Age (years), mean (SD) | 58.6 (14.0) | 50.5 (11.1) 2 | 55.5 (15.2) 3 | 66.6 (11.1) 2,3 | <0.001 |
| Cigarette smoking, n (%) | 82 (78) | 24 (65) | 19 (86) | 39 (85) | 0.05 |
| Alcohol consumption, n (%) | 67 (64) | 19 (51) | 17 (77) | 31 (67) | 0.11 |
| RSI score, mean (SD) | 5.9 (3.8) | 8.1 (5.3) 2 | 6.4 (3.7) | 5.6 (3.8) 2 | 0.04 |
| Pathological characteristics | |||||
| Tis, n (%) | ‒ | ‒ | ‒ | 3 (6) | ‒ |
| T1, n (%) | ‒ | ‒ | ‒ | 23 (49) | ‒ |
| T2, n (%) | ‒ | ‒ | ‒ | 15 (32) | ‒ |
| T3, n (%) | ‒ | ‒ | ‒ | 3 (6) | ‒ |
| T4, n (%) | ‒ | ‒ | ‒ | 3 (6) | ‒ |
| N0, n (%) | ‒ | ‒ | ‒ | 45 (96) | ‒ |
| N1, n (%) | ‒ | ‒ | ‒ | 1 (2) | ‒ |
| N2, n (%) | ‒ | ‒ | ‒ | 1 (2) | ‒ |
Abbreviations: RSI: Reflux Symptom Index; SD: standard deviation; VFL: vocal fold leukoplakia; VP: vocal polyp. 1 Data were compared using one-way analysis of variance with post-hoc Tukey’s honestly significant difference tests for continuous variables, and the chi-square test for categorical variables. 2 p-Value < 0.05 when the variable in the VP subgroup was compared with the VFL or laryngeal cancer subgroup. 3 p-Value < 0.05 when the variable in the VFL subgroup was compared with the laryngeal cancer subgroup. Significant p-values are marked in bold.