Table 4.
Predictive values of variables of interest for the risk of primary laryngeal cancer.
| Variables | Odds Ratio (95% CI) 1 | p-Value | Odds Ratio (95% CI) 2 | p-Value |
|---|---|---|---|---|
| Model | Univariate analysis | Multivariate analysis | ||
| Age | 1.10 (1.06–1.15) | <0.001 | 1.11 (1.06–1.16) | <0.001 |
| Male sex | 2.58 (0.66–10.14) | 0.18 | 0.84 (0.14–4.98) | 0.85 |
| Cigarette smoking | 2.07 (0.77–5.57) | 0.15 | 2.40 (0.66–8.70) | 0.18 |
| Alcohol consumption | 1.32 (0.59–2.96) | 0.50 | 0.92 (0.34–2.53) | 0.87 |
| Helicobacter pylori DNA positivity | <0.001 (<0.001–) | >0.99 | <0.001 (<0.001–) | >0.99 |
| Helicobacter pylori antigen positivity | 1.29 (0.08–21.18) | 0.86 | 0.46 (0.03–8.13) | 0.60 |
| RSI score | 0.90 (0.82–0.996) | 0.04 | 0.96 (0.86–0.1.07) | 0.46 |
| Expression of E-cadherin | 1.00 (1.00–1.01) | 0.34 | 1.00 (0.99–1.01) | 0.75 |
| Expression of CD1d | 1.01 (1.00–1.02) | 0.08 | 1.00 (0.99–1.01) | 0.59 |
Abbreviations: CI: confidence interval; RSI: Reflux Symptom Index; SD: standard deviation; VFL: vocal fold leukoplakia; VP: vocal polyp. 1 The univariate logistic regression model. 2 The multivariate logistic regression model with adjustment for age, male sex, cigarette smoking, and/or alcohol consumption. Significant p-values are marked in bold.