Table 7.

Chemical structures of oximes with non-kinase targets and mechanisms of action.

Compound	Molecular Target/Mechanism	Ref.
32	Dual inhibitor of HNE and Pr3	[15]
33	CCR5 antagonist	[169,170]
34	GluR6 antagonist, amelioration of inflammatory hyperalgesia	[171,172]
35	TRPA1 and TRPV1 antagonist	[14]
36	TRPA1 antagonist	[173,174]
37	TRPA1 antagonist	[173,174]
38	ASIC blocker, attenuation of pathophysiological nociceptive behaviors in CFA-inflamed and CCI rats	[175]
39	Binds directly to two components of the mitochondrial permeability pore, the VDAC, and translocator protein; inhibits MPTP opening	[176]
40	Binds to Hsp90 and provides a significant decrease in HIF-1α expression	[177]