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. 2021 May 22;11(6):447. doi: 10.3390/jpm11060447

Table 1.

The clinical characteristics of study subjects stratified by health literacy in CKD patients.

Entire Cohort
N = 208
Sufficient/Excellent
N = 97
Inadequate/Limited/Problematic
N = 111
p-Value
Demographics
Age (year) 63.2 ± 12.8 59.8 ± 14.2 66.2 ± 10.5 <0.001
Sex (male, %) 58.7 56.7 60.4 0.59
Smoke (yes, %) 7.7 5.2 9.9 0.20
Alcohol (yes, %) 4.8 5.2 4.5 0.83
Marriage (yes, %) 79.3 73.2 84.7 0.04
Currently working (yes, %) 40.9 44.3 37.8 0.34
Education (high school or above, %) 66.8 83.5 52.3 <0.001
Hypertension (yes, %) 60.1 60.8 59.5 0.84
Diabetes mellitus (yes, %) 35.1 29.9 39.6 0.14
Heart disease (yes, %) 18.3 13.4 22.5 0.09
Gout (yes, %) 15.4 17.5 13.5 0.42
Body mass index (kg/m2) 25.0 ± 3.9 24.2 ± 4.1 25.6 ± 3.7 0.01
Number of health education sessions 13.3 ± 11.1 14.2 ± 11.6 12.5 ± 10.6 0.27
The time of CKD (year) 4.1 ± 4.0 4.4 ± 4.1 3.9 ± 4.0 0.32
ACEI/ARB (yes, %) 37.5 39.2 36.0 0.64
CCB (yes, %) 37.0 37.1 36.9 0.98
β-blocker (yes, %) 27.9 29.9 26.1 0.55
Statin (yes, %) 46.2 40.2 51.4 0.11
Questionnaires
Total scores of self-care behavior 61.0 ± 10.3 63.8 ± 9.3 58.5 ± 10.4 <0.001
Diet 14.6 ± 3.7 15.6 ± 3.1 13.8 ± 4.0 <0.001
Exercise 9.4 ± 3.8 10.0 ± 3.5 8.8 ± 4.0 0.03
Home blood pressure monitoring 6.9 ± 3.2 7.6 ± 3.8 6.2 ± 2.3 0.001
Smoking habit 7.6 ± 2.6 7.9 ± 2.7 7.3 ± 2.6 0.16
Medication adherence 22.6 ± 4.9 22.7 ± 4.5 22.4 ± 5.1 0.66
Health literacy 33.1 ± 7.4 38.8 ± 5.9 28.1 ± 4.2 <0.001
Accessing 31.2 ± 10.0 38.4 ± 7.4 24.9 ± 7.4 <0.001
Understanding 37.8 ± 7.6 42.6 ± 7.7 33.7 ± 4.4 <0.001
Appraising 30.8 ± 9.3 37.0 ± 7.0 25.5 ± 7.5 <0.001
Applying 31.6 ± 9.2 37.6 ± 7.2 26.4 ± 7.5 <0.001
Communication/interaction 34.0 ± 8.2 38.7 ± 7.8 29.8 ± 6.0 <0.001
Laboratory Parameters Entire Cohort
N = 208
Suff icient/Excellent
N = 97
Inadequate/Limited/Problematic
N = 111
p-Value
Blood urea nitrogen (mg/dL) 28.4 (19.1,49.6) 27.6 (17.2,41,3) 31.5 (20.1,54.0) 0.09
eGFR (mL/min/1.73m2) 34.3 ± 25.0 37.3 ± 28.9 31.7 ± 20.9 0.11
Hemoglobin (g/dL) 12.2 ± 2.1 12.0 ± 2.0 12.4 ± 2.2 0.25
Albumin (g/dL) 4.4 (4.1,4.6) 4.4 (4.0,4.6) 4.4 (4.2,4.5) 0.71
Uric acid (mg/dL) 6.3 ± 1.8 6.4 ± 1.9 6.1 ± 1.7 0.28
Cholesterol (mg/dL) 175 ± 42 179 ± 46 172 ± 38 0.20
Triglyceride (mg/dL) 109 (77,152) 103 (75,147) 117 (80,185) 0.22
Glycated hemoglobin (%) 5.9 (5.5,6.5) 5.8 (5.5,6.3) 6.0 (5.5,6.7) 0.06
Urine protein/creatinine ratio (mg/mg) 0.5 (0.2,1.6) 0.4 (0.1,1.6) 0.7 (0.2,1.6) 0.18

Data are expressed as numbers (percentages) for categorical variables and mean ± SD or median (25th, 75th percentile) for continuous variables, as appropriate. Abbreviations—ACEI/ARB: angiotensin-converting enzyme inhibitors/angiotensin II receptor blockers; eGFR: estimated glomerular filtration rate.