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. 2021 May 22;13(6):1768. doi: 10.3390/nu13061768

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Relative Difference in Nominally Significant Metabolites from Untargeted Urine GC/MS during Randomized DASH and Control Feeding Periods. Relative difference represents the ratio of peak areas by GC/MS. Differences are tested using generalized estimating equation models evaluating the difference in log₂ peak areas in non-missing samples obtained during randomized study weeks on either DASH or Control diet. Relative differences re-express absolute log₂ difference coefficients (β) as 2^β. Significance at a false discovery rate (FDR) adjusted p < 0.20 is indicated by an asterisk (*). Metabolites are ordered by statistical significance with the most statistically significant metabolites beginning at the bottom near the x-axis. Several metabolites had between 10–20 imputed values including caffeic acid, gentisic acid, uric acid and threonine.