| TQ | Thymoquinone |
| NS | Nigella sativa |
| RA | Rheumatoid Arthritis |
| MTX | Methotrexate |
| MDA | Malondialdehyde |
| BA | Bioavailability (BA) |
| MAPK | Mitogen-activated protein kinase |
| LPS | Lipopolysaccharides |
| DTX | Docetaxel |
| CBZ | Cabazitaxel |
| HA | Hyaluronic acid |
| PVP | Polyvinylpyrrolidone |
| DMARDs | Disease-modifying antirheumatic drugs |
| PGE2 | Prostaglandin E2 |
| GSSG | Glutathione |
| MMP | Matrix metalloproteinase |
| RANKL | Receptor-activated nuclear factor kappa-B ligand |
| COX | Cyclooxygenase |
| ROS | Reactive oxygen species |
| STAT3 | Signal transducer and activator of transcription-3 |
| PARP | Poly-(ADP-ribose) polymerase |
| Mdm2 | Murine double minute-2 |
| MOMP | Mitochondrial outer membrane permeability |
| TQ-NPs | Thymoquinone Nanoparticles |
| NADPH | Nicotinamide adenine dinucleotide phosphate oxidase |
| IL | Interleukin |
| TNF-α | Tumor necrosis factor alpha |
| TLR | Toll-like receptors |
| NF-κB | Nuclear factor kappa light chain enhancer of activated B cells |
| NLRP3 | NOD-like receptor family pyrin domain containing 3 |
| FCA | Freund’s complete adjuvant |
| PLC1 | Polo-like kinase 1 |
| PI3K | Phosphoinositides, including 3-kinase |
| JAK/STAT | Janus kinase signal transducers and transcription |
| Fe-NTA | Fe (III) nitrilotriacetic acid |
| miRNA | microRNA |
| lncRNA | Long non-coding RNAs |
| PTEN | Phosphatase and tensin homolog |
| Eca109 cells | Esophageal cancer cells |
| miR-34a | MicroRNA-34a |
| MBC | Metastatic breast cancers |
| DTX | Docetaxel |
| PEG | Polyethylene |
| TNBC | Triple negative breast cancer |
| PLL | poly-L-lysine |
| PVP | Polyvinylpyrrolidone |
| NFATc1 | Nuclear factor of activated T-cells, cytoplasmic 1 |
| ROS | Reactive oxygen species |
| fMLF | N-Formylmethionine-leucyl-phenylalanine |
| eEF-2K; | Eukaryotic elongation factor-2 kinase |
| NLRP3 | NACHT, LRR, and pyrin domain-containing protein 3 |
| DOX | Doxorubicin |
| SOD | Superoxide dismutase |
| LC-3 | Light chain 3-II |
| PPAR-γ | Peroxisome proliferator-activated receptor gamma |
| UHRF1 | Ubiquitin-like, containing PHD and RING finger domains-1 |
| p-mTOR | Phosphorylated mechanistic target of rapamycin |
| NFκB | Nuclear factor kappa-light-chain-enhancer of activated B cells |
| 4E-BP1 | Eukaryotic translation initiation factor 4E-binding protein 1 |
| eIF4E | Eukaryotic translation initiation factor 4E |
| p70S6K | Ribosomal protein S6 kinase beta-1 also known as p70S6K kinase |
| PI3K | Phosphoinositides, including 3-kinase |
| IRAK1 | Interleukin-1 receptor-associated kinase 1 |
| FAK | Focal adhesion kinase |
| Hes1 | Hairy and enhancer of split-1 |
| VEGF | Vascular endothelial growth factor |
| IRAK1 | Interleukin-1 receptor-associated kinase 1, |
| TWIST1 | Twist-related protein 1 |
| DNMT1 | DNA Methyltransferase 1, |
| HDAC1 | Histone deacetylase 1 |
| Oct-4 | Octamer binding transcription factor-4 |
| Nestin | Neuroepithelial stem cell protein |
| MDM2 | Mouse double minute 2 homolog |
| p-GSK3β | Glycogen synthase kinase 3 beta |
| TRAIL | Tumor necrosis factor-related apoptosis-inducing ligand |
| IKK1 | Inhibitor of nuclear factor kappa B |
| PRAP | Prolactin receptor associated protein |
| UHRF1 | Ubiquitin-like, containing PHD and RING finger domains 1 |
| HDAC | Histone deacetylases |
| BAX | BCL2 Associated X |
| ZEB1 | Zinc Finger E-Box Binding Homeobox 1 |
| LKB1 | Liver kinase B1 |
| AMPK | AMP-activated protein kinase |
| AIF | Apoptosis-inducing factor |
| ERK1/2 | Extracellular signal-regulated protein kinase |
| CDK-2 | Cyclin-dependent kinase-2; |
| HCC | Hepatocellular carcinoma |
| RANTES | Regulated upon activation normal T cell expressed and presumably secreted |
| RES | Reticuloendothelial system |