Table 1.
Precision and accuracy of iohexol plasma clearance and mGFR calculated by a nonlinear mixed effects model and the simplified method.
| Parameter | Method | Precision (%) | Accuracy (%) | |
|---|---|---|---|---|
| P30 * | P10 * | |||
| CL | NLME SM |
80.9 80.7 |
53 |
12 |
| mGFR | NLME SM |
49.2 53.6 |
71 |
24 |
CL; iohexol plasma clearance, mGFR, measured glomerular filtration rate, NLME; nonlinear mixed effects model, SM; simplified method. Precision was calculated as: 2 × standard deviation/mean × 100%. * The percentage of SM estimates falling within ±30% (P30) or ±10% (P10) of CL calculated by NLME.