Table 4.
Associations of rs17173608 with insulin resistance and severity of CAD.
| OR (95%CI) | |||
|---|---|---|---|
| T2D + CAD | T2D | CAD | |
| Insulin resistance | 1.861 (1.330–2.247) * | 1.458 (0.422–5.042) * | 1.435 (1.080–3.356) * |
| Severity of CAD |
a 1.783 (1.335–2.409) ¥
b 1.822 (1.359–2.870) ¥ |
- |
a 1.905 (1.045–2.866) ¥
b 1.634 (1.322–1.989) ¥ |
* Computed using binary logistic regression analysis. ¥ Computed using multinomial logistic regression analysis. HOMA-IR cut-off point: 7.17. Bold font indicates significance at p < 0.05. Insulin-sensitive (IS) used as the reference group (IS vs. IR) for insulin resistance. SVD was used as the reference group (a SVD vs. DVD, b SVD vs. TVD) for severity of CAD. Adjusted for the covariates age, race, gender, and BMI. OR: odds ratio; CI: confidence interval. ‘-’ indicates not relevant.