Table 1.
Other therapeutic effects of marine organism-derived PDRN.
| Kind of Study | Source | Article Number | Therapeutic Effect |
|---|---|---|---|
| In vitro | O. keta | 1 | Alleviative effect on disease symptoms |
| 1 | Biological effect (Anti-MMP, anti-melanogenesis, activating mitochondrial biogenesis) | ||
| 1 | Dysfunctional tissue treatment | ||
| 1 | OA treatment | ||
| O. mykiss | 1 | Anti-melanogenesis | |
| 1 | OA treatment | ||
| In vivo | O. keta | 1 | Anti-osteonecrosis |
| 1 | Anti-ulcer | ||
| 1 | OA treatment | ||
| 3 | Preventive effect on tissue damage | ||
| 1 | RCTT treatment | ||
| 1 | Tendon tear treatment | ||
| O. mykiss | 1 | Anti-Allodynic | |
| 1 | Bone regeneration | ||
| 1 | OA treatment | ||
| 2 | RCTT treatment | ||
| A. sinensis | 1 | Bone regeneration | |
| 1 | Preventive effect on tissue damage | ||
| Clinical | O. keta | 1 | Adjuvant therapy |
| 1 | Alleviative effect on limb pain | ||
| 1 | Alleviative effect on leg pain | ||
| 1 | Alleviative effect on shoulder pain | ||
| 1 | Anti-osteonecrosis | ||
| 1 | Anti-ulcer | ||
| 2 | CRPS treatment | ||
| 1 | Preventive effect on PHL | ||
| 1 | Preventive effect on scar forming | ||
| O. mykiss | 1 | CRPS treatment | |
| 1 | Dysfunctional tissue treatment | ||
| 1 | RCTT treatment | ||
| 2 | OA treatment | ||
| 1 | Preventive effect on PHL |