Table 1. Baseline characteristics in the study group as a whole (Overall) and according to randomization arm.
| Overall (n = 233) | AZA (n = 114) | MMF (n = 119) | |
|---|---|---|---|
| Recipients | |||
| Female, n (%) | 71 (30) | 30 (26) | 41 (34) |
| Age, years | 52.4 ± 12.5 | 52.5 ± 12.5 | 52.4 ± 12.5 |
| Weight, kg | 69.9 ± 13.7 | 71.6 ± 13.2 | 68.1 ± 14.0 |
| BMI, kg/m2 | 24.2 ± 3.9 | 24.4 ± 3.8 | 23.9 ± 4.1 |
| Double kidney graft, n (%) | 20 (8.6) | 9 (7.9) | 11 (9.2) |
| Systolic blood pressure, mm Hg | 138.1 ± 24.7 | 137.2 ± 21.6 | 139.0 ± 27.5 |
| Diastolic blood pressure, mm Hg | 81.7 ± 12.5 | 81.6 ± 11.6 | 81.9 ± 13.3 |
| Hypertension, n (%) | 76 (41.5) | 41 (45.6) | 35 (37.6) |
| PRA >20%, n (%) | 2 (0.9) | 2 (1.8) | 0 (0.0) |
| Duration of dialysis, months | 53.3 ± 34.2 | 51.6 ± 28.4 | 55.0 ± 39.0 |
| Primary cause of renal failure, n (%) | |||
| Diabetes mellitus | 4 (1.7) | 2 (1.8) | 2 (1.7) |
| Glomerulonephritis | 52 (22.3) | 24 (21.1) | 28 (23.5) |
| Hypertension, renovascular disease | 18 (7.7) | 10 (8.8) | 8 (6.7) |
| Polycystic kidney disease | 50 (21.5) | 27 (23.7) | 23 (19.3) |
| Pyelonephritis/Interstitial nephritis | 5 (2.1) | 4 (3.5) | 1 (0.8) |
| Systemic disease | 6 (2.6) | 2 (1.8) | 4 (3.4) |
| Urinary tract alteration | 15 (6.4) | 5 (4.4) | 10 (8.4) |
| Other | 36 (15.5) | 13 (11.4) | 23 (19.3) |
| Uncertain | 47 (20.2) | 27 (23.7) | 20 (11.6) |
| Donors | |||
| Female, n (%) | 113 (48.5) | 57 (50.0) | 56 (47.1) |
| Age, years | 51.2 ± 14.9 | 50.1 ± 14.9 | 52.3 ± 14.4 |
| Weight, kg | 72.1 ± 16.8 | 71.3 ± 17.7 | 72.9 ± 15.8 |
| HLA A mismatches, n (%) | |||
| 0 | 38 (16.3) | 18 (15.8) | 20 (16.8) |
| 1 | 124 (53.2) | 64 (56.1) | 60 (50.4) |
| 2 | 71 (30.5) | 32 (28.0) | 39 (32.8) |
| HLA B mismatches, n (%) | |||
| 0 | 30 (12.9) | 16 (14.0) | 14 (11.8) |
| 1 | 100 (42.9) | 46 (40.4) | 54 (45.4) |
| 2 | 103 (44.2) | 52 (45.6) | 51 (42.9) |
| HLA DR mismatches, n (%) | |||
| 0 | 31 (13.3) | 14 (12.3) | 17 (14.3) |
| 1 | 122 (52.4) | 62 (54.4) | 60 (50.4) |
| 2 | 80 (34.3) | 38 (33.3) | 42 (35.3) |
Data are number (percent) or mean ± SD.
AZA, azathioprine; BMI, body mass index; HLA, human leukocyte antigen; MMF, mycophenolate mofetil; PRA, panel reactive antibody; SD, standard deviation.