Fig 3. EBOV VP24 protein expression inhibits STAT3 responses to OSM.

COS7 cells co-transfected to express the indicated proteins were treated 24 h post-transfection with or without OSM (10 ng/ml, 30 min) before live-cell CLSM analysis (A) to determine the Fn/c for STAT3-mCherry (B; mean ± SEM; n ≥ 35 cells for each condition; results are from a single assay representative of two independent assays). Scale bars, 30 μm. RABV N, rabies virus N-protein. Statistical analysis used Student’s t-test; ****, p < 0.0001.