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. 2021 Jun 24;16(6):e0251646. doi: 10.1371/journal.pone.0251646

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© 2021 Hsieh et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 3 — Microscopic image of the pancreas of (A) untreated rats (N, control group), (B) streptozotocin (STZ)-treated rats (DM, STZ group), and (C–E) STZ + Probioglu^TM-treated rats (DM1X: STZ + 1× Probioglu^TM group, 5.17 × 10⁹ CFU kg^-1 d^-1; DM5X: STZ + 5× Probioglu^TM group, 2.58 × 10¹⁰ CFU kg^-1 d^-1; DM10X: STZ + 10× Probioglu^TM group, 5.17 × 10¹⁰ CFU kg^-1 d^-1) at the end of the experimental period. (F) Mean β-cell mass in each group at the end of the experimental period. Each group consisted of 8 rats in this study. * indicates significant differences compared with the control: p < 0.05.