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. 2021 Jun 24;16(6):e0251646. doi: 10.1371/journal.pone.0251646

Table 2. Insulin levels of rats in each group at weeks 0, 2, 4, 6, and 8.

Week Control (μg l-1) STZ (μg l-1) STZ + 1× ProbiogluTM (μg l-1) STZ + 5× ProbiogluTM (μg l-1) STZ + 10× ProbiogluTM (μg l-1)
0 0.90 ± 0.05 0.90 ± 0.06 0.93 ± 0.04 0.91 ± 0.05 0.90 ± 0.06
2 0.92 ± 0.03 1.93 ± 0.09# 1.89 ± 0.08 # 1.69 ± 0.13#* 1.50 ± 0.2 #*
4 0.95 ± 0.03 2.35 ± 0.28# 2.13 ± 0.10#* 1.76 ± 0.14#* 1.56 ± 0.19#*
6 1.01 ± 0.04 2.42 ± 0.29# 2.20 ± 0.07#* 1.97 ± 0.16#* 1.63 ± 0.16#*
8 1.08 ± 0.03 3.38 ± 0.15# 2.61 ± 0.10#* 2.35 ± 0.06#* 2.18 ± 0.12#*

Untreated rats (control group), streptozotocin (STZ)-treated rats (STZ group), and STZ + ProbiogluTM-treated rats (STZ + 1× ProbiogluTM group, 5.17 × 109 CFU kg-1 d-1; STZ + 5× ProbiogluTM group, 2.58 × 1010 CFU kg-1 d-1; STZ + 10× ProbiogluTM group, 5.17 × 1010 CFU kg-1 d-1). Each group consisted of 8 rats in this study.

* indicates a significant difference compared with the STZ group at p < 0.05

# represents a significant difference compared to the control group at p < 0.05.