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. 2021 Jun 24;16(6):e0253687. doi: 10.1371/journal.pone.0253687

Table 1. Repeatability and accuracy evaluation of SensiScreen® EGFR Liquid assays: Number of copies mutated for Exon 19 deletion, T790M or L858R.

Template Number of mutated copies detected Total
0 1 2 ≥3
Exon 19 deletion c.2235-2249del (Glu746-Ala750del) 25 77 102
T790M c.2369C>T (p.T790M) 20 82 102
L858R c.2573T>G (p.L858R) 23 79 102
Poisson (λ = 1) NA 37.5 64.5 102
37.5 18.8 8.2
Poisson (λ = 1.5) NA 22.8 79.2 102
34.1 25.6 19.5

Abbreviations: EGFR, Epidermal growth factor receptor; NA, not available.