Table 2. Overview of the EGFR phenotypes detected by the Therascreen® (QIAGEN) versus SensiScreen® EGFR Liquid assay (Pentabase) and IOT® Oncomine cell-free nucleic acids assay (Thermo Fisher Scientific) using cohort I and agreement or disagreement between platforms (N = 34).
SensiScreen® EGFR Liquid assay (PentaBase) IOT® Oncomine cell-free nucleic acids assay (Thermo Fisher Scientific) | |||||||
---|---|---|---|---|---|---|---|
TheraScreen® (QIAGEN) | T790M & Ex19del. | T790M & L858R | WT | T790M | Ex19del. | L858R | L861Q |
T790M & Ex19del. | 9 | - | - | - | - | - | - |
T790M & L858R | - | 3 | - | - | - | - | - |
WT | - | - | 13 | - | - | 2 | - |
T790M | - | - | - | 1 | - | - | - |
Ex19del. | - | - | - | - | 4 | - | - |
L858R | - | - | - | - | - | 1 | - |
L861Q | - | - | - | - | - | - | 1 |
Abbreviations: EGFR, Epidermal growth factor receptor; del, deletion; WT, wild type.