Table 1.
Oxygen consumption rates of symmetrical derivatives in L6 rat myoblast cells.
 | |||||||
|---|---|---|---|---|---|---|---|
| Entry | R | % of BAM15 OCRa | EC50, μM | Entry | R | % of BAM15 OCRa | EC50, μM |
| BAM15 |  |
100%b | 0.49 ± 0.06 | 8q |  |
NA | -- |
| 8a |  |
33%b | 2.3 ± 0.7 | 8r |  |
NA | -- |
| 8b |  |
22%c | 2.1 ± 1.3 | 8s |  |
NA | -- |
| 8c |  |
59%c | >20 | 8t |  |
21%b | 3.9 ± 1.1 |
| 8d |  |
NA | -- | 8u |  |
18%b | >100 |
| 8e |  |
43%c | >100 | 8v |  |
8%b | 2.2 ± 0.4 |
| 8f |  |
14%c | >100 | 8w |  |
NA | -- |
| 8g |  |
NA | -- | 8x |  |
5%b | <3 |
| 8h |  |
45%c | 10.1 ± 0.7 | 8y |  |
27%b | 8.8 ± 3.2 |
| 8i |  |
NA | -- | 8z |  |
NA | -- |
| 8j |  |
NA | -- | 8aa |  |
17%b | 1.1 ± 0.4 |
| 8k |  |
NA | -- | 8ab |  |
7%b | <1 μM |
| 8l |  |
NA | -- | 8ac |  |
NA | -- |
| 8m |  |
53%c | 1.1 ± 0.2 | 8ad |  |
0.5%b | <1 μM |
| 8n |  |
14%c | <5 | 8ae |  |
1%b | 1.7 ± 0.3 |
| 8o |  |
39%c | 1.0 ± 0.3 | 8af |  |
0.3%b | <1 μM |
| 8p |  |
28%c | 0.7 ± 0.1 | 8ag |  |
5%b | 6.1 ± 2.6 |
a
Integrated area under OCR dose curve above baseline relative to that of BAM15 expressed as percent. NA = No Activity.
b
Highest tested concentration is 200 μM. BAM15 was tested up to 200 μM.
c
Highest tested concentration is 50 μM. BAM15 was tested up to 50 μM.