Table 2.
Compound | Minimum Inhibitory Concentration (µM) | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
E.c. 1 | E.c. 2 | P.a. | S.a. | S.e. | B.c. | |||||||
D | L | D | L | D | L | D | L | D | L | D | L | |
4a | >200 | 100 | >200 | 100 | >200 | 200 | >200 | 100 | >200 | 200 | >200 | 200 |
4b | >200 | >200 | >200 | 100 | 200 | 200 | 100 | 12.5 | 100 | 12.5 | 100 | 50 |
5 | >200 | >200 | >200 | >200 | >200 | >200 | >200 | 100 | >200 | >200 | >200 | >200 |
5a | >200 | >200 | >200 | >200 | >200 | >200 | >200 | >200 | >200 | 200 | >200 | >200 |
5b * | >200 | >200 | >200 | >200 | >200 | 200 | >200 | 200 | >200 | 200 | >200 | 200 |
6a | >200 | 50 | >200 | 25 | >200 | 200 | 50 | 6.25 | 200 | 12.5 | >200 | 100 |
6b | ND | ND | ND | ND | ND | ND | 25 | 3.12 | 6.25 | 0.78 | 25 | 6.25 |
7a | >200 | 200 | >200 | 100 | >200 | >200 | 50 | 6.25 | 25 | 6.25 | 100 | 50 |
7b | >200 | >200 | >200 | >200 | >200 | >200 | 6.25 | 0.78 | 6.25 | 0.78 | 12.5 | 3.12 |
8a | >200 | 100 | >200 | 50 | >200 | 100 | 25 | 0.78 | 12.5 | 1.56 | 25 | 12.5 |
8b | >200 | 200 | >200 | 100 | >200 | 200 | 50 | 0.39 | 12.5 | 0.78 | 50 | 6.25 |
9a | >200 | 100 | >200 | 50 | >200 | >200 | >200 | 25 | >200 | 12.5 | >200 | 200 |
9b | >200 | >200 | >200 | >200 | 25 | 25 | 6.25 | 1.56 | 12.5 | 1.56 | 6.25 | 6.25 |
10 | >200 | 100 | >200 | 50 | >200 | 12.5 | >200 | 50 | >200 | 100 | >200 | >200 |
10a | >200 | >200 | >200 | >200 | >200 | 200 | >200 | 200 | >200 | 100 | >200 | >200 |
10b | >200 | >200 | >200 | >200 | >200 | >200 | 100 | 50 | >200 | 12.5 | >200 | >200 |
SAPyR | >200 | 200 | >200 | >200 | >200 | 50 | >200 | 50 | 200 | 25 | >200 | 50 |
* Compound obtained with a purity of 70%, mixed with 30% of compound 5. ND: Not data, compounds not soluble at the concentrations.