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. 2021 May 24;12(6):798. doi: 10.3390/genes12060798

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Linkage analysis using chromosomal microarray. (A) Single nucleotide polymorphisms (SNP) duo image for chromosome 1 showing identity by state (sharing one allele) for the whole chromosome. Whole genome comparison confirmed child-parent relationship. Note: Chromosome 1 SNPduo Output A_Culture CVS–B_Proband Mother Average Identity by State (IBS):1.84; (B) SNP duo for chromosome X between the foetus and the X0 cell line showing IBS0, that is sharing no alleles for most of the chromosome including the FMR1 gene. Note: Chromosome X SNPduo Output A_Cultured CVS–B_Proband Mother Average IBS:1.1.547.