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. 2021 May 24;11(6):939. doi: 10.3390/diagnostics11060939

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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MFC. Parallel time sequence of ICGA (a,c,e) and FA (b,d,f) during recurrence. Top pair (a,b) show early ICGA and FA frames, showing extended hypofluorescent area on ICGA, while FA is practically normal. Middle pair (c,d) of images show intermediate phase of ICGA and FA (about 10 min) with more extended and well-visible zones of hypofluorescent choriocapillaris nonperfusion on ICGA, while FA shows leakage and staining. Bottom images (e,f) corresponding to late ICGA hypofluorescent areas causing retinal ischaemia and reactional retinal vessel hyperpermeability following the same mechanism as in APMPPE/AMIC.