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. 2021 May 24;11(6):462. doi: 10.3390/jpm11060462

Table 3.

Risk factors for major complications (Grade III Clavien–Dindo) of ortho-vascular surgery in the patients included in this series.

Variables Cut Off
n. Events/pts
Hazard Ratio (95%CI)
Cut Off
n. Events/pts
Hazard Ratio (95% CI)
p-Value
Age <65 years >65 years 0.9641
17/57 (29.8%) 5/17 (29.4%)
HR 1.0231 HR 0.9775
Gender Female Male 0.0914
14/37 (37.8%) 8/37 (21.6%)
HR 2.0658 HR 0.4841
Cardiovascular risk factors Yes No 0.8347
13/45 (28.9%) 9/29 (31.0%)
HR 0.9124 HR 1.0960
Type 2 diabetes mellitus Yes No 0.7487
1/4 (25.0%) 21/70 (30.0%)
HR 1.3288 HR 0.7526
Obesity Yes No 0.1726
5/16 (31.2%) 17/58 (29.3%)
HR 2.0448 HR 0.8547
Preoperative radiotherapy Yes No 0.1
8/16 (50.0%) 14/58 (24.1%)
HR 2.3397 HR 0.4274
Neoplasia volume <100 mL >100 mL 0.6754
12/38 (31.6%) 10/36 (27.8%)
HR 1.1961 HR 0.8360
Intervention time Less 4 h >4 h 0.0364 *
6/35 (17.1%) 16/39 (41.0%)
HR 0.4083 HR 2.4491
Vascular bypass Yes No 0.2772
4/9 (44.4%) 18/65 (27.7%)
HR 2.1040 HR 0.4753
Flap (yes vs. no) Yes No 0.2984
8/21 (38.1%) 14/53 (26.4%)
HR 1.6540 HR 0.6046
Tumor site (pelvis vs. other sites) Pelvis Other sites 0.0564 *
6/10 (60.0%) 16/64 (25.0%)
HR 3.0753 HR 0.3252

* Statistically significant.