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. 2021 May 24;11(6):1384. doi: 10.3390/nano11061384

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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AuNP-based colorimetric assays. (a) Crosslinking hybridization assay leading to color change upon the detection of specific DNA hybridization. (b) Non-crosslinking method causing the aggregation of the NPs in the absence of a complementary target. (c) Unmodified NP-based colorimetric assay in which the ssDNA stabilizes the AuNPs against aggregation, and NPs undergo aggregation in the presence of dsDNA. Reprinted from ref. [136], under the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0) (accessed on 24 April 2021).