Figure 3.

Difference of stoichiometric coefficients between wildtype (WT) and all mutations. The stoichiometric coefficients for all metabolites participating in the viral biomass objective function (VBOF) are compared. WT stoichiometric coefficients are indicated in red, the mean stoichiometric coefficients of all mutation variants are indicated in orange, including standard deviations (black). If the difference of the stoichiometric coefficients between WT and mutation variants was more than 0.001, the difference is indicated above the bars. The stoichiometric coefficients for the metabolites ATP, ADP and PPi, are higher compared to the other coefficients. The mutation variants’ mean coefficients show little deviation. Additionally, the differences between the stoichiometric coefficients of WT and mutation variants are very small.