Figure 4.

Difference of stoichiometric coefficients between wildtype (WT) and the individual mutations. The deviation between WT and the mean of the individual mutation variants was calculated. Higher stoichiometric coefficients in the mutation compared to the WT are indicated in blue, while lower stoichiometric coefficients are indicated in red. Based on similar sequence length for the mutation variants B.1.1.7 and B.1.1.28 and resulting similar total viral molar masses, a pattern emerges, which is most apparent for the stoichiometric coefficients of ATP and ADP. This pattern, however, is not present for all stoichiometric coefficients. The coefficient for l-serine, for example, is only decreased in the mutation variant B.1.1.7 based on two mutations in two structural proteins. Overall, the deviations from the WT are very small.