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. 2021 May 25;10(6):1309. doi: 10.3390/cells10061309
AD Alzheimer’s Disease
amyloid β peptide
NFT neurofibrillary tangle
ROS reactive oxygen species
RNS reactive nitrogen species
Nrf2 nuclear-factor erythroid 2-related factor
ARE antioxidant response element
NF-κΒ nuclear factor κΒ
MAPK mitogen-activated protein kinase
IL-6 interleukin 6
LPS lipopolysaccharide
EGCG epigallocatechin-3-gallate
ERK extracellular signal-regulated kinase
APP amyloid precursor protein
SP senile plaques
AICD APP intracellular domain
BACE beta-site amyloid precursor protein cleaving enzyme
CTF-β carboxy-terminal fragment beta
PP2A protein phosphatase 2A
CDK-5 cyclin-dependent kinase 5
GSK-3 glycogen synthase kinase-3
ACh acetylcholine
AChE acetylcholinesterase
ChAT choline acetyltransferase
BDNF brain-derived neurotrophic factor
PKC protein kinase C
NGF nerve growth factor
PPAR-α peroxisome proliferator-activated receptor alpha
AChT acetylcholine transferase
sAPPa soluble amyloid precursor protein a
MEPA methanolic extract of Phyllanthus acidus
EGb Ginkgo biloba
CAT catalase
SOD superoxide dismutase
GSH glutathione
GST glutathione S-transferase
BuChE butyrylcholinesterase
T2D type II diabetes
AGE aged garlic extract