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. 2021 Jun 24;336:252–261. doi: 10.1016/j.jconrel.2021.06.033

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© 2021 The Author(s)

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Fig. 3 — Therapeutic efficacy of LEAF-4L6715 in a mouse model of sepsis. The Kaplan-Meier curves represent the therapeutic efficacy of LEAF-4L6715 in mice that underwent CLP. Log-rank tests were performed to compare the survival of the treated mice to that of the control group.