Table 2.
Univariate and multivariate Cox proportional hazards regression models evaluating PNI, CONUT, and other risk factors for the entire patient cohort (n=237).
| Analysis | Univariate | Multivariate | |||||
|---|---|---|---|---|---|---|---|
| Covariate | HR | 95% CI | p-value | HR | 95% CI | p-value | |
| CONUT | > 3 points | 2.1 | 1.6 – 2.9 | <0.001 | 1.3 | 0.9 – 2.0 | 0.201 |
| PNI | ≤ 36 points | 2.9 | 2.1 – 3.9 | <0.001 | 1.9 | 1.2 – 3.0 | 0.003 |
| Age | ≥ 70 years | 1.1 | 0.8 – 1.4 | 0.620 | |||
| AFP | > 200 ng/ml | 1.3 | 1.0 – 1.8 | 0.081 | |||
| Bilirubin level | ≥ 1.2 mg/dl | 2.4 | 1.8 – 3.2 | <0.001 | 1.9 | 1.4 – 2.6 | <0.001 |
| AST level | > 31 U/L | 2.0 | 1.0 – 4.1 | 0.054 | |||
| ALT level | ≥ 35 U/L | 1.1 | 0.8 – 1.5 | 0.550 | |||
| INR level | > 1.2 | 1.2 | 0.9 – 1.7 | 0.260 | |||
| Platelet count | > 150/nl | 1.3 | 0.9 – 1.8 | 0.140 | |||
| Tumor number | ≥ 2 | 1.3 | 0.9 – 1.9 | 0.110 | |||
| Max. lesion size | > 5.0 cm | 1.2 | 0.9 – 1.7 | 0.160 | |||
Statistically significant p-values are depicted in bold.