Table 3.
Univariate and multivariate Cox proportional hazards regression models evaluating the PNI, CONUT, and other risk factors for the subgroup of recommended TACE candidates (n=126).
| Analysis | Univariate | Multivariate | |||||
|---|---|---|---|---|---|---|---|
| Covariate | HR | 95% CI | p-value | HR | 95% CI | p-value | |
| CONUT | > 7 points | 2.4 | 1.4 – 4.1 | 0.001 | 1.6 | 0.9 – 2.9 | 0.085 |
| PNI | ≤ 39 points | 2.1 | 1.3 – 3.1 | <0.001 | 1.6 | 1.1 – 2.5 | 0.040 |
| Age | ≥ 70 years | 0.9 | 0.6 – 1.3 | 0.550 | |||
| AFP | > 200 ng/ml | 1.0 | 0.6 – 1.5 | 0.910 | |||
| Bilirubin level | ≥ 1.2 mg/dl | 2.2 | 1.5 – 3.4 | <0.001 | 1.8 | 1.1 – 2.8 | 0.011 |
| AST level | > 31 U/L | 1.2 | 0.5 – 2.7 | 0.690 | |||
| ALT level | ≥ 35 U/L | 1.1 | 0.7 – 1.7 | 0.600 | |||
| INR level | > 1.2 | 1.1 | 0.7 – 1.8 | 0.600 | |||
| Platelet count | > 150/nl | 1.0 | 0.6 – 1.6 | 0.840 | |||
| Max. lesion size | > 5.0 cm | 1.4 | 0.9 – 2.1 | 0.180 | |||
Statistically significant p-values are depicted in bold.