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. 2021 Jun 18;8(3):ENEURO.0504-20.2021. doi: 10.1523/ENEURO.0504-20.2021

Table 1.

Clinical and neuropathological information




Case
Sex Age
(years)
Cause of death Postmortem
delay (h)
Braak
stage
CERAD
stage
Neuropsychological diagnosis
AB1 Male 45 Lung cancer <1 0 0 No recorded neurologic alterations
AB3 Male 53 Bladder carcinoma 3.5 0 0 No recorded neurologic alterations
IF10 Male 66 Bronchopneumonia and
cardiac failure
2 0 0 No recorded neurologic alterations
M16 Male 40 Traffic accident 3 0 0 No recorded neurologic alterations
IF1 Female 80 - 2 IV B No evidence of cognitive
impairment and dementia
VK11 Female 87 Respiratory inflammation 1.5 III−IV A Dementia
VK16 Female 88 - 2.5 VI C Dementia
VK22 Female 86 - 2 V C Dementia

Braak stages (Braak and Braak, 1991): III, NFTs in EC and closely related areas; III−IV, NFTs abundant in amygdala and hippocampus; extending slightly into association cortex; V−VI, NFTs widely distributed throughout the neocortex and ultimately involving primary motor and sensory areas. CERAD stages (Mirra et al., 1991): A, low density of neuritic plaques; B, intermediate density of neuritic plaques; C, high density of neuritic plaques. -, not available.