Table 1.
Baseline demographics.
| COVID-19 ICU patients (n = 103) | Current treatment group (LMWH protocol) (n = 57) | |
|---|---|---|
| Demographics | ||
| Age (years) | 68.20 ± 11.32 | 67.63 ± 12.65 |
| Gender (male/female) | 46/57 | 30/27 |
| BMI (kg/m2) | 28.03 ± 5.19 | 28.41 ± 5.20 |
|
| ||
| Comorbidities | ||
| Smoking | 5 (4.9%) | 0 (0.0%) |
| Arterial hypertension | 62 (60.2%) | 33 (57.9%) |
| Diabetes | 33 (32.0%) | 18 (31.6%) |
| Respiratory disease | 20 (19.4%) | 8 (14.0%) |
| Malignancy | 11 (10.7%) | 7 (12.3%) |
| Chronic kidney disease | 15 (14.6%) | 9 (15.8%) |
| Chronic liver disease | 3 (2.9%) | 2 (3.5%) |
| Cardiovascular disease | 39 (37.9%) | 27 (47.4%) |
| Chronic bowel disease | 8 (7.8%) | 4 (7.0%) |
| Chronic nervous disease | 1 (1.0%) | 1 (1.8%) |
| Cerebrovascular disease | 18 (17.5%) | 12 (21.1%) |
| Haematological disease | 9 (8.7%) | 5 (8.8%) |
| Rheumatological disease | 8 (7.8%) | 4 (7.0%) |
| Dementia | 2 (1.9%) | 1 (1.8%) |
| HIV/AIDS | 0 (0.0%) | 0 (0.0%) |
|
| ||
| Clinical data on admission | ||
| Fever | 77 (74.8%) | 36 (63.2%) |
| Cough | 82 (80.4%) | 39 (69.6%) |
| Dyspnoea | 75 (73.5%) | 38 (67.9%) |
| Sputum production | 11 (10.8%) | 6 (10.7%) |
| Myalgia | 52 (51.0%) | 28 (50.0%) |
| Headache | 10 (9.8%) | 4 (7.1%) |
| Diarrhoea | 19 (18.6%) | 12 (21.4%) |
| Respiratory rate | 25.11 ± 6.66 | 26.00 ± 7.41 |
| Systolic blood pressure | 142.91 ± 26.70 | 144.72 ± 25.97 |
| Diastolic blood pressure | 90.73 ± 17.12 | 88.39 ± 14.29 |
| Heart rate | 88.44 ± 19.79 | |
| Urine output day 1 | 1275.21 ± 822.00 | 1282.35 ± 726.99 |
| GCS (total) | 14.22 ± 1.33 | 14.52 ± 1.16 |
| P/F ratio | 117.44 ± 78.95 | 124.65 ± 61.48 |
|
| ||
| Laboratory findings | ||
| Red blood cell count (1012/l) | 4.09 ± 0.74 | 3.84 ± 0.74 |
| White blood cell count (109/l) | 8.77 ± 5.08 | 10.89 ± 7.63 |
| Lymphocytes (%) | 19.91 ± 36.28 | 29.45 ± 47.90 |
| Platelets (109/l) | 246.15 ± 101.72 | 239.64 ± 100.24 |
| Bilirubin (mg/l) | 0.66 ± 0.59 | 0.72 ± 0.76 |
|
| ||
| Length of stay (before ICU) (days) | 3.10 ± 5.12 | 3.95 ± 6.27 |
| SOFA (on ICU admission) | 4.52 ± 2.99 | 4.18 ± 2.51 |
| APACHE II (on ICU admission) | 12.49 ± 4.94 | 11.96 ± 6.10 |
| APACHE IV (on ICU admission) | 46.21 ± 15.24 | 42.61 ± 14.73 |
| Clinical frailty index | 4.01 ± 1.58 | 3.91 ± 1.65 |
Results are displayed in mean ± SD or as numbers (%).