Table 2.
Summary of baseline characteristics of patients included in the analysis
| Study | n | Age (years) median (min, max) | Body weight (kg) median (min, max) | eGFR (ml/min/1.73 m2) median (min, max) | sUA (mg/dL) median (min, max) | Sex (males) n (%) | Race: Caucasian n (%) | Race: Black n (%) | Race: Asian n (%) | Race: other n (%) |
|---|---|---|---|---|---|---|---|---|---|---|
| D5495C00001 | 36 | 41 (20, 63) | 85.7 (57.7, 121.3) | 91.4 (52.8, 128) | 7.1 (5.8, 9.6) | 35 (97.2) | 14 (38.9) | 17 (47.2) | 2 (5.6) | 3 (8.3) |
| D5495C00006 | 21 | 38 (27, 48) | 72.25 (58.75, 90.75) | 103 (70.4, 119.1) | 6 (4.2, 10.7) | 19 (90.5) | 0 (0) | 0 (0) | 21 (100) | 0 (0) |
| D5495C00007 | 32 | 62 (43, 79) | 90.4 (52.6, 136.3) | 55.9 (31.6, 109.9) | 7.5 (6, 13.3) | 22 (68.8) | 22 (68.8) | 6 (18.8) | 3 (9.4) | 1 (3.1) |
| RDEA3170-104 | 48 | 31.5 (21, 53) | 70.4 (54.9, 101.7) | 113.4 (78, 138.3) | 5.7 (4, 8.1) | 48 (100) | 5 (10.4) | 3 (6.2) | 40 (83.3) | 0 (0) |
| RDEA3170-105 | 23 | 35 (21, 48) | 87.9 (65.8, 115.9) | 98.3 (75.7, 117.7) | 6.4 (5, 9.1) | 23 (100) | 15 (65.2) | 7 (30.4) | 0 (0) | 1 (4.3) |
| RDEA3170-107 | 12 | 51.5 (29, 69) | 99.7 (80.9, 126.3) | 84.3 (54.1, 102.9) | 8.6 (7.1, 9.6) | 12 (100) | 7 (58.3) | 4 (33.3) | 0 (0) | 1 (8.3) |
| RDEA3170-108 | 31 | 61 (35, 81) | 82.6 (59, 122) | 74 (12.3, 106.1) | 6.7 (4.1, 12.4) | 31 (100) | 23 (74.2) | 7 (22.6) | 0 (0) | 1 (3.2) |
| RDEA3170-110 | 15 | 44 (25, 62) | 90.9 (65.4, 129.4) | 99.2 (74.9, 134.3) | 5.3 (4.4, 6.5) | 15 (100) | 11 (73.3) | 2 (13.3) | 0 (0) | 2 (13.3) |
| RDEA3170-112 | 40 | 35.5 (24, 56) | 86.1 (59.2, 126.8) | 99.6 (78.1, 131.6) | 5.7 (4.2, 7.4) | 40 (100) | 22 (55) | 17 (42.5) | 1 (2.5) | 0 (0) |
| RDEA3170-204 | 64 | 48 (29, 71) | 98.65 (63.8, 138.7) | 89.7 (57.4, 121.1) | 8.8 (5.5, 12.3) | 64 (100) | 43 (67.2) | 7 (10.9) | 14 (21.9) | 0 (0) |
| RDEA3170-205 | 72 | 46 (21, 67) | 75.45 (58.3, 115.6) | 105.6 (76.8, 133.2) | 8.6 (7.5, 12.7) | 72 (100) | 0 (0) | 0 (0) | 72 (100) | 0 (0) |
| RDEA3170-206 | 40 | 48 (28, 74) | 95.5 (63.1, 147.6) | 89.9 (55.1, 125.6) | 9 (6.7, 10.7) | 39 (97.5) | 30 (75) | 6 (15) | 4 (10) | 0 (0) |
| All subjects | 434 | 45 (20, 81) | 84 (52.6, 147.6) | 97 (12.3, 138.3) | 7.6 (4, 13.3) | 420 (96.8) | 192 (44.2) | 76 (17.5) | 157 (36.2) | 9 (2.1) |
eGFR estimated glomerular filtration rate, sUA serum uric acid