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. 2020 Jun 18;41(6):1325–1336. doi: 10.1007/s10571-020-00905-3

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© The Author(s) 2020, corrected publication 2021

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Fig. 4 — Effect of LPS- or HpX-derived EVs on cultured glia cells. EVs from LPS- (a) or HpX- (b) treated animals were added to the culture medium of HMC3 glia cells at the indicated concentrations. After 1 h the conditioned medium was assayed for TNF-α, IL1ß and IL6. Results are the means of 6 independent observations. Error bars indicate S.D. #Below detection limit of the assay. ***p < 0.001. In the case that values were below detection limit of the assay, no statistical analysis could be performed