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. 2020 Jun 18;41(6):1325–1336. doi: 10.1007/s10571-020-00905-3

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© The Author(s) 2020, corrected publication 2021

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Fig. 5 — Cytokine release to the CSF after intracerebroventricular injection of LPS- or HPx-derived EVs. EVs (10 µg) from LPS- or HpX-treated animals were administered by intracerebroventricular (icv) injection to healthy rats. After 1 h CSF was taken and assayed for TNF-α, IL1ß and IL6. Results are the means of 6 independent observations. Error bars indicate S.D. ***p < 0.001