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. 2020 Jun 18;41(6):1325–1336. doi: 10.1007/s10571-020-00905-3

Fig. 6.

Fig. 6

Cytokine release to the CSF after peripheral intravenous injection of LPS- or HpX-derived EVs. EVs (250 µg) from LPS- or HpX-treated animals were administered by intravenous injection via the femoral vene to healthy rats. After 1 h CSF was taken and assayed for TNF-α, IL1ß and IL6. Results are the means of 6 independent observations. Error bars indicate S.D. #Below detection limit of the assay. ***p < 0.001. In the case that values were below detection limit of the assay, no statistical analysis could be performed