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Effect of physostigmine
| Reduction of cytokine release | ||||
|---|---|---|---|---|
| TNFα (%) | IL1β (%) | IL6 (%) | ||
| Exosome donors | LPS | 26.5 | 20.9 | 26.9 |
| HpX | 22.6 | 18.7 | 28.0 | |
| Sub-study I | LPS | 26.2 | 22.2 | 23.7 |
| HpX | 28.6 | – | 24.4 | |
| Sub-study II | LPS | 29.6 | 18.8 | 22.9 |
| HpX | 25.7 | 24.0 | 26.7 | |
| Sub-study III | LPS | 21.2 | 22.3 | 29.7 |
| HpX | 21.7 | – | 26.4 | |
