Table 1.

Representative Inpatient Schedule

Day	2 Outpatient Days	Move-in	1	2	3	4	5
Condition			Acute Effects	‘Abstinence Initiation’*			Acute Effects
Cannabis			Exp-Administration	Self-Administration			Exp-Administration
Lorcaserin (mg BID)	10	10	10	10	10	10	10
Day	6	7	8	9	10	11	Move-out
Condition	Abstinence			‘Relapse’
Cannabis	None			Self-Administration
Lorcaserin (mg BID)	10	10	10	10	10	10	None

Cannabis = 7.0% THC. Exp-Administration = Experimenter-administered: Each participant smoked 3 puffs of cannabis at no financial cost. Self-administration: Participants had the option of purchasing individual cannabis puffs. ‘Abstinence Initiation’: Cannabis self-administration following 0 days of cannabis abstinence. ‘Relapse:’ Self-administration following 3 days of cannabis abstinence.

^*Order of abstinence initiation and withdrawal/relapse conditions was counterbalanced, as were doses of lorcaserin (0, 10 mg BID).