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. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: Genes Immun. 2021 May 1;22(2):65–74. doi: 10.1038/s41435-021-00130-y

Table 3.

Cohort-specific immunogenetic findings with various supporting evidence.

Locus Variant (allele or aa residue) Setting Association Reference(s)
HLA-A A*36:01a Zambian SPs Promoting HIV-1 transmission Ref. [17]
HLA-B Alleles sharingb Both partners Promoting HIV-1 transmission Ref. [2]
KIR2DS4 Full-length allele *001c Zambian SPs Promoting HIV-1 transmission Ref. [18]
a

Observation was confirmed multiple times in expanded cohorts (e.g., Figure 2), with clear impact on viral load in the SP partners.

b

Supported by experimental evidence [8].

c

The only allele encoding a functional, full-length receptor, with implications for inflammation mediated through natural killer cells [7].