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. Author manuscript; available in PMC: 2022 Jun 25.
Published in final edited form as: Circ Res. 2021 Apr 23;129(1):50–62. doi: 10.1161/CIRCRESAHA.120.317532

Figure 4.

Figure 4.

Blood pressure by telemetry in control (n=6) and mutant sPRR mice (n=5). A-C: at baseline and following Ang-II infusion at 400 ng/kg/min for 14 days. A: 24 hour systolic blood pressure; B: 24 hour diastolic blood pressure, *P <0.001 by mixed effects model; C: systolic blood pressure at baseline, days 7 and 14 following Ang-II infusion, P value calculated using Student’s unpaired t-test at each time point; D-F: following mouse recombinant sPRR infusion (rsPRR, 30μg/kg/day) and concurrent Ang-II infusion at 400 ng/kg/min (control n=3, all other groups n=4/group). D: 24 hour systolic blood pressure; E: 24 hour diastolic blood pressure using mixed effects model; F: systolic blood pressure following recombinant sPRR prior to and after Ang-II infusion using one-way ANOVA with Tukey post-hoc test at each time point.