Table 1.

Echocardiography in control & mutant sPRR mice at baseline and following 12-days of Ang-II infusion.

	Baseline		Post-Ang-II
	Control (N=8)	Mutant (N=9)	Control (N=6)	Mutant (N=8)
Heart rate (bpm)	365 ± 9	339 ± 13	361 ± 18	359 ± 12
Cardiac output (ml/min/g)	0.4 ± 0.02	0.4 ± 0.02	0.3 ± 0.05	0.4 ± 0.03
Ejection fraction (%)	47.1 ± 2.6	45.6 ± 1.9	44.9 ± 5.9	48.6 ± 2.8
Fractional shortening (%)	23.8 ± 3.5	22.3 ± 1.0	22.4 ± 3.5	24.2 ± 1.6
Left ventricular mass (mg/g)	2.9 ± 0.1	3.3 ± 0.2 *	3.0 ± 0.1	3.3 ± 0.1
Stroke volume (μl/g)	1.0 ± 0.04	1.0 ± 0.07	0.9 ± 0.09	1.1 ± 0.06 *
Volume (end-diastolic, μl/g)	2.2 ± 0.2	2.3 ± 0.2	2.0 ± 0.09	2.3 ± 0.09 *
Volume (end-systolic, μl/g)	1.2 ± 0.2	1.2 ± 0.1	1.1 ± 0.2	1.2 ± 0.1
E/A	1.8 ± 0.1	1.5 ± 0.1	2.0 ± 0.3	1.7 ± 0.1

^*P <0.05 vs control mice by Student’s unpaired t-test.