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. 2021 Jun 24;11:13251. doi: 10.1038/s41598-021-92784-x

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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CD206 + and CD86 + MHCII + CD206- cells in MNP subsets are dynamically regulated after IRI. MNP composition was monitored over a 10 day time course in a kidney injury model of IRI (n = 9 for sham, n = 10 for 3 h, n = 10 for 1d, n = 12 for 3d, n = 6 for 7d, n = 7 for 10d): Data are depicted as pie charts with their size corresponding to the amount of total cells (A, cell number is given as mean in cells per mg kidney) or plotted on a time axis grouped into CD206 + and CD86 + MHCII + CD206- cells (B) or MNP subsets (C, red = CD86 + MHCII + CD206-, green = CD206 +). Cell numbers for each time point in (C) were compared by unpaired t test of y = ln(y) transformed data *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.