Fig. 4.

Effect of losartan on mean blood pressure over study days 1–15. X-axis is day of treatment, and y-axis is mean arterial pressure (MAP) in mmHg. Placebo is in red and losartan in blue with 95% CIs at each assessment. While losartan did not statistically significantly affect these outcomes overall or at any time point, a non-significant reduction of up to 10 mmHg was observed at approximately day 5. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)