Table 1.
Trial demographics and comorbidities following intention to treat by randomization group. Binary and categorical variable summaries reflect No (%) {No Missing}, and continuous variable summaries reflect Median [25th, 75th percentiles] {No Missing}.
| Randomization Group |
||
|---|---|---|
| Placebo | Losartan | |
| Number Enrolled | 59 | 58 |
| Site of Enrollment | ||
| M Health | 24 (40.7%) | 23 (39.7%) |
| Hennepin | 25 (42.4%) | 26 (44.8%) |
| Mayo | 10 (16.9%) | 9 (15.5%) |
| Demographics | ||
| Female | 25 (42.4%) {0} | 33 (56.9%) {0} |
| Age | 37 [27, 46] {0} | 38 [29, 51] {1} |
| 18 – 34 | 27 (45.8%) | 20 (34.5%) |
| 35 – 54 | 23 (39%) | 31 (53.4%) |
| 55 – 64 | 9 (15.3%) | 3 (5.2%) |
| 65 – 89 | 0 (0%) | 3 (5.2%) |
| Missing | 0 (0%) | 1 (1.7%) |
| BMI | 27.5 [24.5, 32.0] {0} | 28.3 [24.8, 32.6] {0} |
| Normal weight (18.5 – 24.9) | 18 (30.5%) | 16 (27.6%) |
| Overweight (25 – 29.9) | 22 (37.3%) | 19 (32.8%) |
| Obese (30 – 55) | 19 (32.2%) | 23 (39.7%) |
| Race | ||
| Caucasian | 39 (66.1%) | 45 (77.6%) |
| Black or African American | 4 (6.8%) | 4 (6.9%) |
| Asian | 5 (8.5%) | 1 (1.7%) |
| Hispanic | 5 (8.5%) | 5 (8.6%) |
| Other/Unknown | 6 (10.2%) | 3 (5.2%) |
| Ethnicity | ||
| Non-Hispanic or Latino | 49 (83.1%) | 50 (86.2%) |
| Hispanic or Latino | 6 (10.2%) | 4 (6.9%) |
| Unknown | 4 (6.8%) | 4 (6.9%) |
| Insurance Type | ||
| Uninsured | 4 (6.8%) {0} | 5 (8.6%) {0} |
| Medicaid | 3 (5.1%) {0} | 3 (5.2%) {0} |
| Medicare | 0 (0%) {0} | 1 (1.7%) {0} |
| Private | 52 (88.1%) {0} | 49 (84.5%) {0} |
| Comorbid Conditions | ||
| Coronary Artery Disease | 0 (0%) {0} | 0 (0%) {1} |
| Hypertension | 3 (5.1%) {0} | 6 (10.3%) {1} |
| Congestive Heart Failure | 0 (0%) {0} | 0 (0%) {1} |
| Pulmonary Hypertension | 0 (0%) {0} | 0 (0%) {1} |
| Asthma | 8 (13.6%) {0} | 4 (6.9%) {1} |
| Chronic Obstructive Pulmonary Disorder | 0 (0%) {0} | 0 (0%) {1} |
| Chronic Bronchitis | 0 (0%) {0} | 0 (0%) {1} |
| Obstructive Sleep Apnea | 5 (8.5%) {0} | 3 (5.2%) {1} |
| Diabetes Mellitus | 3 (5.1%) {0} | 4 (6.9%) {1} |
| Tobacco or Nicotine User | 5 (8.5%) {0} | 7 (12.1%) {1} |