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. 2021 Jun 24;11:13286. doi: 10.1038/s41598-021-92693-z

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Optical coherence tomography and optical coherence tomography angiography of case 5 before half dose photodynamic therapy (PDT) (a). One month after treatment (b), the subretinal fluid was reabsorbed completely and choroidal neovascularization (CNV) network was more clearly visible. 3-year after first half-dose PDT(c), the size of CNV had enlarged from 0.763 mm² one month after treatment to 1.025 mm² three years after treatment.