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. 2021 Jun 24;11:13270. doi: 10.1038/s41598-021-92577-2

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Building scale-free networks using wiring rules. (a–f) Wiring rules generating the scale-free graph in (f) with b = 4, where the rule (top) initializes the set of colored edges (bottom). Edges created by each wiring rule are colored in (f), visualizing how individual rules add together to the final network. (g, h) Cytoscape visualizations of scale free graphs generated by the model for b = 5 and b = 6, respectively. Node size scales with degree, and the link weights illustrate the number of individual wiring rules coding for the individual edge.