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. 2021 Jun 11;8:657087. doi: 10.3389/fmolb.2021.657087

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Copyright © 2021 Zhao, Cai, Zhang, He, Peng, Tu, Peng, Wang, Yu and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Association of the risk signature with clinicopathological features from both LUAD and LUSC. (A) Heat map of different clinicopathological characteristics from high- vs. low-risk LUADs stratified by percent spliced index (PSI) of the AS events. (B) Association of the risk scores with clinicopathological features from LUAD. (C) Heat map of different clinicopathological features of from high- vs. low-risk stratified by the PSI of the AS events. (D) Association of the risk scores with clinicopathological features from LUSC. ***p < 0.001, **p < 0.01, and *p < 0.05. AS, alternative splicing; LUAD, lung adenocarcinoma; LUSC, lung squamous cell carcinoma; PSI, percent spliced in index.