TABLE 1.
The univariate and multivariate cox regression analysis of clinicopathological data from TCGA-LUAD and LUSC.
| Variables | Univariate analysis | Multivariate analysis | ||||||
|---|---|---|---|---|---|---|---|---|
| HR | HR.95L | HR.95H | Adj-p | HR | HR.95L | HR.95H | Adj-p | |
| LUAD | ||||||||
| Age (≥65/<65) | 1.111 | 0.823 | 1.500 | 4.92E-01 | 1.204 | 0.884 | 1.640 | 2.38E-01 |
| Gender (female/male) | 1.111 | 0.826 | 1.494 | 4.86E-01 | 1.077 | 0.791 | 1.467 | 6.37E-01 |
| Smoking (yes/no) | 0.864 | 0.440 | 1.697 | 6.72E-01 | 1.863 | 0.878 | 3.955 | 1.05E-01 |
| TNM stage (I + II/III + IV) | 1.635 | 1.422 | 1.881 | *** | 1.564 | 1.187 | 2.062 | *** |
| T | 1.548 | 1.296 | 1.848 | *** | 1.066 | 0.865 | 1.315 | 5.48E-01 |
| N | 1.962 | 1.461 | 2.634 | *** | 1.108 | 0.722 | 1.701 | 6.39E-01 |
| M | 2.181 | 1.302 | 3.653 | ** | 0.740 | 0.355 | 1.543 | 4.21E-01 |
| Risk score | 1.441 | 1.346 | 1.543 | *** | 1.390 | 1.281 | 1.508 | *** |
| LUSC | ||||||||
| Age ( ≥ 65/<65) | 1.017 | 0.999 | 1.035 | 6.40E-02 | 1.028 | 1.007 | 1.050 | * |
| Gender (female/male) | 1.095 | 0.782 | 1.534 | 5.97E-01 | 1.225 | 0.834 | 1.800 | 3.01E-01 |
| TNM stage (I + II/III + IV) | 1.283 | 1.079 | 1.526 | ** | 1.132 | 0.726 | 1.765 | 5.83E-01 |
| T | 1.352 | 1.121 | 1.630 | ** | 1.434 | 1.083 | 1.897 | ** |
| N | 1.170 | 0.952 | 1.438 | 1.35E-01 | 1.092 | 0.735 | 1.622 | 6.62E-01 |
| M | 2.455 | 0.905 | 6.659 | 7.77E-02 | 1.111 | 0.279 | 4.420 | 8.82E-01 |
| Risk score | 1.054 | 1.040 | 1.069 | *** | 1.884 | 1.473 | 2.386 | *** |
LUAD: lung adenocarcinoma; LUSC: lung squamous cell carcinoma; TNM: tumor-node metastasis; HR: hazard ratio.* represents p < 0.05; ** represents p < 0.05; *** represents p < 0.001.