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. 2021 Jun 11;11:635324. doi: 10.3389/fonc.2021.635324

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Copyright © 2021 Huo, Wu and Zang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The building process of the seven immune gene prognostic signature in the TCGA cohort. (A) The forrest plot of the univariate Cox analysis. (B) The corrplot of the prognostic related genes. (C) Lasso penalized COX regression analysis. (D) The optimal cutoff determined by 5-year time-depend ROC curve. (E, F) The Kaplan–Meier survival analysis and time‑dependent ROC analysis of the signature for predicting the OS of patients in the TCGA cohort. (G) The risk score distribution of patients in in the TCGA cohort.