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. 2021 Jun 11;12:678505. doi: 10.3389/fneur.2021.678505

Table 2.

Primary and secondary efficacy outcomes and safety outcomes.

Overall Propensity Score Matched
BMT BMT + EVT BMT BMT + EVT
n = 133 n = 270 p n = 73 n = 73 p
Primary Outcome (n, %)
mRS 0–3 45 (33.8) 87 (26.7) 0.248 29 (41.4) 31 (43.1) 0.844
Secondary Outcome (n, %)
mRS 0–2 33 (24.8) 51 (18.9) 0.323 23 (32.9) 19 (26.4) 0.398
mRS 0–1 18 (13.5) 26 (9.6) 0.506 14 (20.0) 9 (12.5) 0.225
mRS (median, IQR) 5 (2–6) 5 (3–6) 0.284 4 (2–6) 4 (2–5) 0.962
mRS (median, IQR)
0–6 h onset to admission6–24 h onset to admission>24 h onset to admissionunknown onset 5 (3–6) 4 (2–5) 3 (2–6) 6 (4–6) 5 (3–6) 5 (4–6) 4.5 (2–6) 5 (4–6) 0.952 0.496 0.517 0.479 4 (2–6) 4 (2–5) – 4 (2–5) 4 (3–6) – 0.4670.330 –
mRS (median, IQR)
<10 NIHSS on admission≥10 NIHSS on admission 3 (1.75–5) 6 (5–6) 3 (2–5) 5 (4–6) 0.3510.037 3 (1–5) 5 (5–6) 3 (1–5) 5 (4–6) 0.9400.207
mRS (median, IQR)
<70 years≥70 years 4 (2–6) 5 (4–6) 5 (2–6) 5 (4–6) 0.5020.358 4 (2–5) 4.5 (2–6) 4 (2–5) 4 (3–6) 0.6770.685
Safety outcome (n, %)
Mortality 44 (33.8) 94 (36.2) 0.730 18 (24.7) 14 (19.1) 0.549
Surgical decompression 3 (2.3) 11 (4.1) 0.336 3 (4.1) 2 (2.7) 0.999
Pneumonia 109 (82.0) 73 (27.0) 0.047 15 (20.5) 17 (23.3) 0.842
Brain edema 7 (5.3) 24 (8.9) 0.199 5 (6.8) 5 (6.8) 1
Intracerebral bleeding 1 (0.8) 4 (1.5) 0.534 0 (0) 2 (2.7) 0.497
Cerebral arterial embolism 4 (3.0) 13 (4.8) 0.396 2 (2.7) 4 (5.5) 0.681

BMT, best medical treatment; EVT, endovascular thrombectomy; IQR, interquartile range; NIHSS, National Institutes of Health Stroke Scale; mRS, modified rankin scale.