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. 2021 Jun 11;12:622948. doi: 10.3389/fphar.2021.622948

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Copyright © 2021 Tang, Ding, Duan, Li, Lu, Zhou, Shi, Lu, Shen, Zhuang, Sun, Zhou, Zhu, Li and Yu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The linear regression analysis was used to compare the predicted trough concentration of vancomycin PPK software SmartDose and JPKD in ARC group and non-ARC group. (A) Prediction of SmartDose for trough concentration in ARC group (r = 0.8286, p < 0.001). (B) Prediction of JPKD for trough concentration in ARC group (r = 0.8845, p < 0.001). (C) Prediction of SmartDose for trough concentration in non-ARC group (r = 0.8877, p < 0.001). (D) Prediction of JPKD for trough concentration in non-ARC group (r = 0.8633, p < 0.001).