Table 3.

Main demographic and clinical characteristics of patients in selected studies.

Focus score
First Author,Year	Mean Age, Years	N	F	Xerostomia	Xeroftalmia	Glandular swelling	Arthritis	Renal involvement	Hematological involvement	Lung involvement	Cutaneous involvement	PNS involvement	CNS involvement	Lymphoma	Muscular involvement	RP
Wise and Woodruff (23)		187	164
FS ≤ 1	53.6	111	97	67	70	10		6		9	12
FS > 1	56	76	67	47	47	19		5		12	10
Carubbi et al (24)		383	368
FS = 0		72	69	71	70	28	51	2	25	8	9	7	1	4	0	19
FS = 1		74	73	70	60	14	44	3	10	7	10	2	5	2	1	21
FS > 1		237	226	212	225	79	150	4	43	16	17	12	3	8	4	61
Daniels et al. (25)		1,726
FS ≥ 1		730		669	624
FS < 1		328		292	292
Reksten et al. (19)		141
FS−	49	18
FS+	51	97
GC
Carubbi et al. (20)	52	104	98
GC−	55	46	42			3	19	2		6	5	5	1	0	1	16
GC+	49	58	56			19	28	2		6	7	5	4	2	1	18
He et al. (21)		126	124
GC−		90	88			17	40									16
GC+	49.92	36	36			8	14									6
Jonsson et al. (18)	54	169
GC−	56	122				32
GC+	52	47				14
Lee et al. (22)		93	91
GC−	45.08	65	64			5	43	1						0		15
GC+	43.39	28	27			3	14	2						1		6
Reksten et al. (19)		97
GC-	53	70
GC+	46	27

N, numbers of included patients; F, number of female; PNS, peripheral nervous system; CNS, central nervous system; RP, Raynaud’s phneomena.