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. 2021 Jun 11;11:682445. doi: 10.3389/fonc.2021.682445

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Copyright © 2021 Fanale, Fiorino, Incorvaia, Dimino, Filorizzo, Bono, Cancelliere, Calò, Brando, Corsini, Sciacchitano, Magrin, Pivetti, Pedone, Madonia, Cucinella, Badalamenti, Russo and Bazan

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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BRCA1 functional domains and gene location of BRCA1 Variants of Uncertain Significance in BC and/or OC patients. BCCR, Breast Cancer Cluster Region; BRCT, BRCA1 C-terminus domain; NLS, nuclear localization sequence; OCCR, Ovarian Cancer Cluster Region; SCD, serine cluster domain; VUS, Variant of Uncertain Significance.